Loughlin, Wendy A. and Marshall, Raymond L. and Fairfull-Smith, Kathryn E. and Healy, Peter C. (2005) (Z,Z)-3,6-Bis[(3,4,5-trimethoxyphenyl)-methylene]piperazine-2,5-dione. Acta Crystallographica Section E: Structure Reports Online, 61 (5). pp. 1443-1445.

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The title compound, C24H26N2O8, is a derivative of neihumicin, a cytotoxic antibiotic from Micromonospora neihuensis. The compound crystallizes as discrete molecules with crystallographic inversion symmetry. Intermolecular N-HO hydrogen bonds yield polymeric chains along the c axis. The trimethoxyphenylmethylene side chain is found to be in a Z configuration about the C=C double bond.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: © 2005 International Union of Crystallography. The Creative Commons Attribution Licence applies to all articles published in Acta Crystallographica Section E and open-access articles published in other IUCr journals. Under this licence the authors retain the copyright of their article, but allow others to reuse and copy the article provided the original authors and source are cited.
Faculty/School / Institute/Centre: Historic - Faculty of Sciences - Department of Biological and Physical Sciences (Up to 30 Jun 2013)
Faculty/School / Institute/Centre: Historic - Faculty of Sciences - Department of Biological and Physical Sciences (Up to 30 Jun 2013)
Date Deposited: 17 Feb 2010 10:29
Last Modified: 02 Aug 2021 04:24
Uncontrolled Keywords: Micromonospora neihuensis; neihumicin
Fields of Research (2008): 03 Chemical Sciences > 0306 Physical Chemistry (incl. Structural) > 030606 Structural Chemistry and Spectroscopy
03 Chemical Sciences > 0399 Other Chemical Sciences > 039999 Chemical Sciences not elsewhere classified
04 Earth Sciences > 0403 Geology > 040306 Mineralogy and Crystallography
Fields of Research (2020): 34 CHEMICAL SCIENCES > 3403 Macromolecular and materials chemistry > 340399 Macromolecular and materials chemistry not elsewhere classified
34 CHEMICAL SCIENCES > 3499 Other chemical sciences > 349999 Other chemical sciences not elsewhere classified
37 EARTH SCIENCES > 3705 Geology > 370505 Mineralogy and crystallography
Socio-Economic Objectives (2008): E Expanding Knowledge > 97 Expanding Knowledge > 970103 Expanding Knowledge in the Chemical Sciences
Identification Number or DOI: https://doi.org/10.1107/S1600536805012316
URI: http://eprints.usq.edu.au/id/eprint/454

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