The Effect of Resistance Training on Telomere Length in Women Recovering from Breast Cancer

Hagstrom, Amanda D. and Denham, Joshua ORCID: (2018) The Effect of Resistance Training on Telomere Length in Women Recovering from Breast Cancer. Journal of Functional Morphology and Kinesiology, 3 (1):9. pp. 1-7.

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The purpose of this exploratory analysis was to examine the effects of resistance training (RT) on leukocyte telomere length in breast cancer survivors. Samples from 33 breast cancer survivors were analysed following a 16-week RT or usual care intervention (RT: n = 19, control: n = 14). The RT group performed supervised exercise three times per week. Leukocyte telomere length was assessed before and after training using quantitative PCR. Changes in telomere length were analysed using ANCOVA, with the change score being the dependent variable, and the baseline value the covariate. Effect sizes (ES) were calculated via partial eta squared. We found a non-statistically significant change in telomere length, and a small associated ES in the RT group compared to the control group for change in telomere length (p = 0.78, ES = 0.003). Our exploratory study demonstrates that a 16-week RT intervention does not have a significant effect on telomere length in women recovering from breast cancer. Therefore, RT is a safe intervention that does not accelerate biological ageing.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
Faculty/School / Institute/Centre: No Faculty
Faculty/School / Institute/Centre: No Faculty
Date Deposited: 14 Dec 2021 00:08
Last Modified: 04 Aug 2022 23:04
Uncontrolled Keywords: Breast cancer; Resistance training; Telomere
Fields of Research (2008): 06 Biological Sciences > 0604 Genetics > 060499 Genetics not elsewhere classified
11 Medical and Health Sciences > 1106 Human Movement and Sports Science > 110602 Exercise Physiology
Fields of Research (2020): 31 BIOLOGICAL SCIENCES > 3105 Genetics > 310599 Genetics not elsewhere classified
42 HEALTH SCIENCES > 4207 Sports science and exercise > 420702 Exercise physiology
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