Developing a research base for intravenous peripheral cannula re-sites (DRIP trial). A randomised controlled trial of hospital in-patients

Webster, Joan and Lloyd, Sophia and Hopkins, Tracey and Osborne, Sonya ORCID: and Yaxley, Maria (2007) Developing a research base for intravenous peripheral cannula re-sites (DRIP trial). A randomised controlled trial of hospital in-patients. International Journal of Nursing Studies, 44 (5). pp. 664-671. ISSN 0020-7489


Background: There is currently no high grade evidence on which to base decisions about the frequency of intravenous cannula re-sites.

Objective: To assess the safety of changing peripheral venous cannulas when clinically indicated.

Design: Randomised controlled trial.

Setting: A tertiary referral hospital in Brisbane, Australia.

Participants: Two hundred and six hospitalised patients from surgical, medical and orthopaedic wards. Interventions: Peripheral intravenous cannulas were re-sited only when complications occurred (intervention group) or every 3 days (control group).

Main outcome measures: The primary endpoint was any unplanned cannula removal, the secondary outcome was cost.

Results: Forty six patients had unplanned removals in the intervention group compared with 41 in the control group [relative risk 1.12, 95% confidence interval 0.81-1.55 (p = 0.286)], a non-significant difference. Total duration of peripheral cannulation was similar in both groups (mean 123.3 h in the intervention group and 125.9 h in the control group: P = 0.82) but significantly more re-sites occurred in the control group (167 in intervention group, 202 in the control group: p = 0.022). Cost of cannula replacements in the intervention group was AUD$3,183.62 and in the control group AUD$3,837.56 (p = 0.006).

Conclusion: Re-siting peripheral venous cannulas when clinically indicated compared with changing them routinely every 3 days does not lead to more complications and reduces costs.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Permanent restricted access to Published version in accordance with the copyright policy of the publisher.
Faculty/School / Institute/Centre: No Faculty
Faculty/School / Institute/Centre: No Faculty
Date Deposited: 09 Aug 2021 06:09
Last Modified: 09 Aug 2021 06:09
Uncontrolled Keywords: clinical trials; cost and cost analysis; infusions; intravenous
Fields of Research (2008): 11 Medical and Health Sciences > 1110 Nursing > 111003 Clinical Nursing: Secondary (Acute Care)
Fields of Research (2020): 42 HEALTH SCIENCES > 4205 Nursing > 420501 Acute care
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