Acute Effects of Frequent Light-Intensity Standing-Based Exercises That Interrupt 8 Hours of Prolonged Sitting on Postprandial Glucose in Stroke Survivors: A Dose-Escalation Trial

Mackie, Paul and Crowfoot, Gary and Gyawali, Prajwal ORCID: https://orcid.org/0000-0003-0975-5576 and Janssen, Heidi and Holliday, Elizabeth and Dunstan, David and English, Coralie (2021) Acute Effects of Frequent Light-Intensity Standing-Based Exercises That Interrupt 8 Hours of Prolonged Sitting on Postprandial Glucose in Stroke Survivors: A Dose-Escalation Trial. Journal of Physical Activity and Health, 18 (6). pp. 644-652. ISSN 1543-5474


Abstract

Background: Interrupting prolonged sitting can attenuate postprandial glucose responses in overweight adults. The dose–response effect in stroke survivors is unknown. The authors investigated the effects of interrupting 8 hours of prolonged sitting with increasingly frequent bouts of light-intensity standing-based exercises on the postprandial glucose response in stroke survivors.

Methods: Within-participant, laboratory-based, dose-escalation trial. Participants completed three 8-hour conditions: prolonged sitting and 2 experimental conditions. Experimental conditions involved light-intensity standing-based exercises of increasing frequency (2 × 5 min to 6 × 5 min bouts). Postprandial glucose is reported.

Results: Twenty-nine stroke survivors (aged 66 y) participated. Interrupting 8 hours of prolonged sitting with light-intensity standing-based exercises every 90 minutes significantly decreased postprandial glucose (positive incremental area under the curve; −1.1 mmol/L·7 h; 95% confidence interval, −2.0 to −0.1). In the morning (08:00–11:00), postprandial glucose decreased during the 4 × 5 minutes and 6 × 5 minutes conditions (positive incremental area under the curve; −0.8 mmol/L·3 h; 95% confidence interval, −1.3 to −0.3 and −0.8 mmol/L·3 h; 95% confidence interval, −1.5 to −0.2, respectively) compared with prolonged sitting.

Conclusion: Interrupting 8 hours of prolonged sitting at least every 90 minutes with light-intensity standing-based exercises attenuates postprandial glucose in stroke survivors. During the morning, postprandial glucose is attenuated when sitting is interrupted every 60 and 90 minutes.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Faculty/School / Institute/Centre: No Faculty
Faculty/School / Institute/Centre: No Faculty
Date Deposited: 17 Jun 2021 06:19
Last Modified: 22 Oct 2021 00:16
Uncontrolled Keywords: clinical research, exercise, metabolic health
Fields of Research (2008): 11 Medical and Health Sciences > 1103 Clinical Sciences > 110321 Rehabilitation and Therapy (excl. Physiotherapy)
11 Medical and Health Sciences > 1109 Neurosciences > 110904 Neurology and Neuromuscular Diseases
11 Medical and Health Sciences > 1106 Human Movement and Sports Science > 110602 Exercise Physiology
Fields of Research (2020): 32 BIOMEDICAL AND CLINICAL SCIENCES > 3209 Neurosciences > 320905 Neurology and neuromuscular diseases
Socio-Economic Objectives (2008): C Society > 92 Health > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920111 Nervous System and Disorders
Identification Number or DOI: https://doi.org/10.1123/jpah.2020-0516
URI: http://eprints.usq.edu.au/id/eprint/42240

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