Queen Garnet plum juice and raspberry cordial in mildly hypertensive obese or overweight subjects: a randomized, double-blind study

Bhaswant, Maharshi and Brown, Lindsay and Mathai, Michael L. (2019) Queen Garnet plum juice and raspberry cordial in mildly hypertensive obese or overweight subjects: a randomized, double-blind study. Journal of Functional Foods, 56. pp. 119-126. ISSN 1756-4646

Abstract

The anthocyanin, cyanidin 3-glucoside, in Queen Garnet (QG) plums reduced cardiovascular parameters, obesity and inflammation in diet-induced metabolic syndrome in rats. We have now assessed whether QG juice improves cardiovascular and metabolic risk factors and markers of inflammation in mildly hypertensive overweight or obese humans. The 32 subjects were randomly divided into two groups consuming either QG juice or Placebo (raspberry cordial) drinks for 12 weeks. QG juice decreased systolic blood pressure by 12 ± 3 mmHg, diastolic blood pressure by 9 ± 2 mmHg, insulin by 6 ± 3 pmol/L, and leptin by 4 ± 2.5 ng/ml, and increased adiponectin by 3.62 ± 0.28 µg/ml. Cyanidin 3-glucoside is the likely active component of the plum juice, with possible additive effects of other flavonoids such as quercetin glycosides. Thus, QG juice decreased blood pressure and attenuated some risk factors of metabolic syndrome after 12 weeks suggesting that daily consumption could attenuate the development of cardiovascular and metabolic diseases.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Published version cannot be displayed due to copyright restrictions
Faculty/School / Institute/Centre: Current - Faculty of Health, Engineering and Sciences - School of Health and Wellbeing
Date Deposited: 23 May 2019 04:03
Last Modified: 20 Jun 2019 05:55
Uncontrolled Keywords: Queen Garnet plum; Anthocyanins; Cyanidin 3-glucoside; hypertension; obesity
Fields of Research : 11 Medical and Health Sciences > 1111 Nutrition and Dietetics > 111103 Nutritional Physiology
11 Medical and Health Sciences > 1115 Pharmacology and Pharmaceutical Sciences > 111501 Basic Pharmacology
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
Identification Number or DOI: doi.10.1016/j.jff.2019.03.011
URI: http://eprints.usq.edu.au/id/eprint/36272

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