Phomoxins B and C: polyketides from an endophytic fungus of the genus eupenicillium

Davis, Rohan A. and Andjic, Vesna and Kotiw, Michael and Shivas, Roger G. (2005) Phomoxins B and C: polyketides from an endophytic fungus of the genus eupenicillium. Phytochemistry, 66 (23). pp. 2771-2775. ISSN 0031-9422


Chemical investigations of the culture broth from an endophytic fungus Eupenicillium sp. have afforded two natural products phomoxins B (1) and C (2) as well as the previously reported fungal metabolite eupenoxide (3). Compounds 1 and 2 both contain a cyclic carbonate moiety that is rare among natural products. This paper reports the full spectroscopic characterisation of phomoxins B (1) and
C (2) by NMR, UV, IR and MS data. All compounds were inactive against a panel of nosocomial microbes.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Deposited in accordance with the copyright policy of the publisher.
Faculty / Department / School: Historic - Faculty of Sciences - Department of Biological and Physical Sciences
Date Deposited: 23 Jan 2008 01:51
Last Modified: 02 Jul 2013 22:55
Uncontrolled Keywords: endophytic fungus; Eupenicillium sp.; glochidion ferdinandi; natural products; polyketides; phomoxin B; phomoxin C; eupenoxide; cyclic carbonate
Fields of Research : 06 Biological Sciences > 0605 Microbiology > 060505 Mycology
11 Medical and Health Sciences > 1115 Pharmacology and Pharmaceutical Sciences > 111502 Clinical Pharmacology and Therapeutics
03 Chemical Sciences > 0305 Organic Chemistry > 030502 Natural Products Chemistry
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970103 Expanding Knowledge in the Chemical Sciences
Identification Number or DOI: 10.1016/j.phytochem.2005.09.004

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