Using Mahalanobis distance to evaluate recovery in acute stroke

Tehan, Hannah and Witteveen, Kate and Tolan, G. Anne and Tehan, Gerald and Senior, Graeme J. (2017) Using Mahalanobis distance to evaluate recovery in acute stroke. Archives of Clinical Neuropsychology. ISSN 0887-6177

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In the weeks immediately following a stroke, impairments across multiple cognitive domains are pervasive yet there is little literature that explores cognitive recovery during this period. This paper evaluates the use of Mahalanobis distance as a means of statistically evaluating cognitive change at the individual level.
A small battery of standardised neuropsychological tests was administered on five or six occasions across a two week period to the participants recovering from a stroke and a non-stroke control group. Mahalanobis distance was used to evaluate the change profile of those who were recovering from a stroke relative to the non-stroke control.
The outcomes of three patients show that Mahalanobis distance could statistically differentiate recovery, no change, and deterioration from normal repetition effects.
In the acute phase of stroke using Mahalanobis distance it is possible to distinguish between recovery, normal learning, and gerneralised learning deficits thereby identifying likely candidates for further cognitive assessment and rehabilitation.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Accepted version deposited in accordance with the copyright policy of the publisher.
Faculty/School / Institute/Centre: Current - Faculty of Health, Engineering and Sciences - School of Psychology and Counselling
Date Deposited: 27 Mar 2018 05:48
Last Modified: 09 May 2018 00:18
Uncontrolled Keywords: stroke; acute; recovery; Mahalanobis distance
Fields of Research : 11 Medical and Health Sciences > 1109 Neurosciences > 110903 Central Nervous System
17 Psychology and Cognitive Sciences > 1702 Cognitive Sciences > 170201 Computer Perception, Memory and Attention
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
E Expanding Knowledge > 97 Expanding Knowledge > 970117 Expanding Knowledge in Psychology and Cognitive Sciences
Identification Number or DOI: 10.1093/arclin/acx107

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