Systematic review of psychosocial outcomes for patients with advanced melanoma

Dunn, Jeff and Watson, Maggie and Aitken, Joanne F. and Hyde, Melissa K. (2017) Systematic review of psychosocial outcomes for patients with advanced melanoma. Psycho-Oncology, 26 (11). ISSN 1057-9249

Abstract

Background: New advanced melanoma therapies are associated with improved survival; however, quality of survivorship, particularly psychosocial outcomes, for patients overall and those treated with newer therapies is unclear.

Objective: Synthesize qualitative and quantitative evidence about psychosocial outcomes for advanced (stage III/IV) melanoma patients.

Methods: Five databases were searched (01/01/1980 to 31/01/2016). Inclusion criteria were as follows: advanced melanoma patients or sub-group analysis; assessed psychosocial outcomes; and English language.

Results: Fifty-two studies met review criteria (4 qualitative, 48 quantitative). Trials comprise mostly medical not psychosocial interventions, with psychosocial outcomes assessed within broader quality of life measures. Patients receiving chemotherapy or IFN-alpha showed decreased emotional and social function and increased distress. Five trials of newer therapies appeared to show improvements in emotional and social function. Descriptive studies suggest that patients with advanced, versus localized disease, had decreased emotional and social function and increased distress. Contributors to distress were largely unexplored, and no clear framework described coping/adjustment trajectories. Patients with advanced versus localized disease had more supportive care needs, particularly amount, quality, and timing of melanoma-related information, communication with and emotional support from clinicians. Limitations included: lack of theoretical underpinnings guiding study design; inconsistent measurement approaches; small sample sizes; non-representative sampling; and cross-sectional design.

Conclusions: Quality trial evidence is needed to clarify the impact of treatment innovations for advanced melanoma on patients' psychosocial well-being. Survivorship research and subsequent translation of that knowledge into programs and services currently lags behind gains in the medical treatment of advanced melanoma, a troubling circumstance that requires immediate and focused attention.


Statistics for USQ ePrint 32060
Statistics for this ePrint Item
Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Published online 7 Nov 2016. Permanent restricted access to ArticleFirst version, in accordance with the copyright policy of the publisher.
Faculty / Department / School: No Faculty
Date Deposited: 08 Jun 2017 01:54
Last Modified: 21 Dec 2017 03:57
Uncontrolled Keywords: advanced melanoma; cancer; distress; metastatic melanoma; oncology; psychosocial; supportive care; survivorship
Fields of Research : 11 Medical and Health Sciences > 1103 Clinical Sciences > 110319 Psychiatry (incl. Psychotherapy)
11 Medical and Health Sciences > 1112 Oncology and Carcinogenesis > 111299 Oncology and Carcinogenesis not elsewhere classified
17 Psychology and Cognitive Sciences > 1701 Psychology > 170106 Health, Clinical and Counselling Psychology
Identification Number or DOI: 10.1002/pon.4290
URI: http://eprints.usq.edu.au/id/eprint/32060

Actions (login required)

View Item Archive Repository Staff Only