Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease

Dempsey, Paddy C. and Owen, Neville and Biddle, Stuart J. H. ORCID: and Dunstan, David W. (2014) Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease. Current Diabetes Reports, 14 (9). pp. 1-11. ISSN 1534-4827


Modern human environments are vastly different from those of our forebears. Rapidly advancing technology in transportation, communications, workplaces, and home entertainment confer a wealth of benefits, but increasingly come with costs to human health. Sedentary behavior - too much sitting as distinct from too little physical activity - contributes adversely to cardiometabolic health outcomes and premature mortality. Findings from observational epidemiology have been synthesized in meta-analyses, and evidence is now shifting into the realm of experimental trials with the aim of identifying novel mechanisms and potential causal relationships. We discuss recent observational and experimental evidence that makes a compelling case for reducing and breaking up prolonged sitting time in both the primary prevention and disease management contexts. We also highlight future research needs, the opportunities for developing targeted interventions, and the potential of population-wide initiatives designed to address too much sitting as a health risk.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: No
Item Status: Live Archive
Additional Information: Published version cannot be displayed due to copyright restrictions.
Faculty/School / Institute/Centre: No Faculty
Faculty/School / Institute/Centre: No Faculty
Date Deposited: 24 Jul 2017 06:01
Last Modified: 08 Feb 2018 04:13
Uncontrolled Keywords: breaks in sedentary time; cardiometabolic risk; cardiovascular disease; mortality; physical activity; physical inactivity; sedentary behavior; sitting time; TV viewing time; type 2 diabetes; cardiovascular diseases; diabetes mellitus; humans; motor activity; public policy; risk factors; sedentary lifestyle; public health, social medicine and epidemiology; cardiovascular diseases and cardiovascular surgery; clinical and experimental biochemistry; endocrinology; health policy, economics and management
Fields of Research (2008): 11 Medical and Health Sciences > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified
Fields of Research (2020): 42 HEALTH SCIENCES > 4299 Other health sciences > 429999 Other health sciences not elsewhere classified
Socio-Economic Objectives (2008): E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
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