Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome

Panchal, Sunil K. and Wanyonyi, Stephen and Brown, Lindsay (2017) Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome. Current Hypertension Reports, 19 (3). pp. 10-20. ISSN 1522-6417


Trace metals play an important role in the proper functioning of carbohydrate and lipid metabolism. Some of the trace metals are thus essential for maintaining homeostasis, while deficiency of these trace metals can cause disorders with metabolic and physiological imbalances. This article concentrates on three trace metals (selenium, vanadium, and chromium) that may play crucial roles in controlling blood glucose concentrations
possibly through their insulin-mimetic effects. For these trace metals, the level of evidence available for their health effects as supplements is weak. Thus, their potential is not fully exploited for the target of metabolic syndrome, a constellation that increases
the risk for cardiovascular disease and type 2 diabetes.
Given that the prevalence of metabolic syndrome is increasing throughout the world, a simpler option of interventions with food supplemented with well-studied trace metals could serve as an answer to this problem. The oxidation state and coordination chemistry play crucial roles in defining the responses to these
trace metals, so further research is warranted to understand fully their metabolic and cardiovascular effects in human metabolic syndrome.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Permanent restricted access to published version, in accordance with the copyright policy of the publisher.
Faculty / Department / School: Current - Faculty of Health, Engineering and Sciences - School of Health and Wellbeing
Date Deposited: 24 Apr 2017 07:58
Last Modified: 17 Apr 2018 01:44
Uncontrolled Keywords: micronutrients, chromium, selenium, vanadium, metabolic syndrome
Fields of Research : 11 Medical and Health Sciences > 1111 Nutrition and Dietetics > 111103 Nutritional Physiology
11 Medical and Health Sciences > 1115 Pharmacology and Pharmaceutical Sciences > 111501 Basic Pharmacology
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
Identification Number or DOI: 10.1007/s11906-017-0701-x

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