Postoperative early major and minor complications in laparoscopic vertical sleeve gastrectomy (LVSG) versus laparoscopic Roux-en-Y gastric bypass (LRYGB) procedures: a meta-analysis and systematic review

Osland, Emma and Yunus, Rossita Mohamad and Khan, Shahjahan and Alodat, Tareq and Memon, Breda and Memon, Muhammed Ashraf (2016) Postoperative early major and minor complications in laparoscopic vertical sleeve gastrectomy (LVSG) versus laparoscopic Roux-en-Y gastric bypass (LRYGB) procedures: a meta-analysis and systematic review. Obesity Surgery, 26 (10). 2273- 2284. ISSN 0960-8923

Abstract

Purpose: Laparoscopic roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG), have been proposed as cost effective strategies to manage obesity related chronic disease. The aim of this systematic review and meta-analysis was to compare the “early postoperative complication rate i.e within 30 days” reported from randomized control trials (RCTs) comparing these two procedures. Material and Methods: RCTs comparing the early complication rates following LSG and LRYGB between 2000 and 2015 were selected from PubMed, Medline, Embase, Science Citation Index, Current Contents, and the Cochrane database. The outcome variables analyzed included 30-day mortality, major and minor complications and interventions required for their management, length of hospital stay, readmission rates, operating time and conversions from laparoscopic to open procedures. Results: Six RCTs involving a total of 703 patients (LSG n=352, LRYGB n=351) reported on major complications. A statistically significant reduction in relative odds of major complications favoring the LSG procedure was noted (p=0.05). Five RCTs representing 643 patients (LSG=322, LRYGB=321) reported minor complications. A non-statically significant reduction in relative odds of 28% favoring the LGS procedure was observed for minor complications (p=0.4). However other outcomes directly related to complications which included reoperation rates, readmission rate, and 30-day mortality rate showed comparable effect size for both surgical procedures. Conclusions: This systematic review and meta-analysis of RCTs suggests that fewer major and minor complications are associated with LSG compared with LRYGB procedure. However this does not translate into higher readmission rate, reoperation rate or 30-day mortality for either procedure.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Published version cannot be displayed due to copyright restrictions.
Faculty / Department / School: Current - Faculty of Health, Engineering and Sciences - School of Agricultural, Computational and Environmental Sciences
Date Deposited: 09 Feb 2017 06:42
Last Modified: 03 May 2017 00:22
Uncontrolled Keywords: bariatric surgery; laparoscopic; sleeve gastrectomy; Roux-en-Y gastric bypass; meta-analysis; systematic review
Fields of Research : 11 Medical and Health Sciences > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified
01 Mathematical Sciences > 0104 Statistics > 010401 Applied Statistics
01 Mathematical Sciences > 0104 Statistics > 010402 Biostatistics
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
E Expanding Knowledge > 97 Expanding Knowledge > 970101 Expanding Knowledge in the Mathematical Sciences
Identification Number or DOI: 10.1007/s11695-016-2101-8
URI: http://eprints.usq.edu.au/id/eprint/30441

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