Whole genome phylogeny of Bacillus by feature frequency profiles (FFP)

Wang, Aisuo and Ash, Gavin J. (2015) Whole genome phylogeny of Bacillus by feature frequency profiles (FFP). Scientific Reports , 5. pp. 1-14. ISSN 2045-2322

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Abstract

Fifty complete Bacillus genome sequences and associated plasmids were compared using the “feature frequency profile” (FFP) method. The resulting whole-genome phylogeny supports the placement of three Bacillus species (B. thuringiensis, B. anthracis and B. cereus) as a single clade. The monophyletic status of B. anthracis was strongly supported by the analysis. FFP proved to be more effective in inferring the phylogeny of Bacillus than methods based on single gene sequences [16s rRNA gene, GryB (gyrase subunit B) and AroE (shikimate-5-dehydrogenase)] analyses. The findings of FFP analysis were verified using kSNP v2 (alignment-free sequence analysis method) and Harvest suite (core genome sequence alignment method).


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: This work is licensed under a Creative Commons Attribution 4.0 International License
Faculty / Department / School: Current - Faculty of Health, Engineering and Sciences - School of Agricultural, Computational and Environmental Sciences
Date Deposited: 01 Sep 2016 04:04
Last Modified: 04 Jun 2018 06:28
Fields of Research : 06 Biological Sciences > 0601 Biochemistry and Cell Biology > 060199 Biochemistry and Cell Biology not elsewhere classified
02 Physical Sciences > 0299 Other Physical Sciences > 029999 Physical Sciences not elsewhere classified
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences
Identification Number or DOI: 10.1038/srep13644
URI: http://eprints.usq.edu.au/id/eprint/29676

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