Sharp, Julie A. and Wanyonyi, Stephen and Modepalli, Vengama and Watt, Ashalyn and Kuruppath, Sanjana and Hinds, Lyn A. and Kumar, Amit and Abud, Helen E. and Lefevre, Christophe and Nicholas, Kevin R. (2017) The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk. General and Comparative Endocrinology, 244. pp. 164-177. ISSN 0016-6480
Abstract
It is now clear that milk has multiple functions; it provides the most appropriate nutrition for growth of the newborn, it delivers a range of bioactives with the potential to stimulate development of the young, it has the capacity to remodel the mammary gland (stimulate growth or signal cell death) and finally milk can provide protection from infection and inflammation when the mammary gland is susceptible to these challenges. There is increasing evidence to support studies using an Australian marsupial, the tammar wallaby (Macropus eugenii), as an interesting and unique model to study milk bioactives. Reproduction in the tammar wallaby is characterized by a short gestation, birth of immature young and a long lactation. All the major milk constituents change substantially and progressively during lactation and these changes have been shown to regulate growth and development of the tammar pouch young and to have roles in mammary gland biology. This review will focus on recent reports examining the control of lactation in the tammar wallaby and the timed delivery of milk bioactivity.
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| Item Type: | Article (Commonwealth Reporting Category C) |
|---|---|
| Refereed: | Yes |
| Item Status: | Live Archive |
| Additional Information: | Accepted version embargoed until 1 September 2019 (24months) in accordance with the copyright policy of the Publisher. Published online 11 August 2016. Permanent restricted access to ArticleFirst version in accordance with the copyright policy of the publisher. |
| Faculty / Department / School: | Current - Faculty of Health, Engineering and Sciences - School of Health and Wellbeing |
| Date Deposited: | 20 Feb 2017 06:42 |
| Last Modified: | 19 Dec 2017 04:00 |
| Uncontrolled Keywords: | lactation, milk, mammary gland, marsupial, monotreme |
| Fields of Research : | 11 Medical and Health Sciences > 1115 Pharmacology and Pharmaceutical Sciences > 111501 Basic Pharmacology |
| Socio-Economic Objective: | D Environment > 96 Environment > 9608 Flora, Fauna and Biodiversity > 960802 Coastal and Estuarine Flora, Fauna and Biodiversity |
| Identification Number or DOI: | 10.1016/j.ygcen.2016.08.007 |
| URI: | http://eprints.usq.edu.au/id/eprint/29620 |
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