Chopin, Lisa and Walpole, Carina and Seim, Inge and Cunningham, Peter and Murray, Rachael and Whiteside, Eliza ORCID: https://orcid.org/0000-0001-9710-7987 and Josh, Peter and Herington, Adrian
(2011)
Ghrelin and cancer.
Molecular and Cellular Endocrinology, 340 (1).
pp. 65-69.
ISSN 0303-7207
Abstract
Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular and immune systems. Ghrelin and its receptor are expressed in a number of cancers and cancer cell lines and may play a role in processes associated with cancer progression, including cell proliferation, apoptosis, and cell invasion and migration.
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