Ghrelin and cancer

Chopin, Lisa and Walpole, Carina and Seim, Inge and Cunningham, Peter and Murray, Rachael and Whiteside, Eliza and Josh, Peter and Herington, Adrian (2011) Ghrelin and cancer. Molecular and Cellular Endocrinology, 340 (1). pp. 65-69. ISSN 0303-7207


Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular and immune systems. Ghrelin and its receptor are expressed in a number of cancers and cancer cell lines and may play a role in processes associated with cancer progression, including cell proliferation, apoptosis, and cell invasion and migration.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: © 2011 Elsevier Ireland Ltd. Permanent restricted access to published version due to publisher copyright policy.
Faculty/School / Institute/Centre: Historic - Faculty of Sciences - Department of Biological and Physical Sciences
Date Deposited: 05 Nov 2014 02:12
Last Modified: 31 Jan 2017 01:46
Uncontrolled Keywords: apoptosis; cancer; cell migration and invasion; ghrelin; growth hormone secretagogue receptor; proliferation
Fields of Research : 11 Medical and Health Sciences > 1112 Oncology and Carcinogenesis > 111201 Cancer Cell Biology
03 Chemical Sciences > 0304 Medicinal and Biomolecular Chemistry > 030406 Proteins and Peptides
11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences
Identification Number or DOI: 10.1016/j.mce.2011.04.013

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