Seaweeds as potential therapeutic interventions for the metabolic syndrome

Kumar, Senthil Arun and Brown, Lindsay (2013) Seaweeds as potential therapeutic interventions for the metabolic syndrome. Reviews in Endocrine and Metabolic Disorders, 14 (3). pp. 299-308. ISSN 1389-9155


Seaweeds are a characteristic part of the traditional diet in countries such as Japan and Korea; these countries also have a lower prevalence of metabolic syndrome than countries such as the USA and Australia. This suggests that seaweeds may contain compounds that reduce the characteristic signs of obesity, diabetes, hypertension, fatty liver and inflammation in the metabolic syndrome. Potentially bioactive compounds from seaweeds include polysaccharides, peptides, pigments, minerals and omega-3 fatty acids. This review emphasises current research on these compounds in isolated cells, animal models and patients. Key problems for future research include chemical characterisation of the bioactive principles, defining pharmacological responses in all aspects of the metabolic syndrome, determining if a therapeutic dose has been administered, and defining oral bioavailability of the active ingredients.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: © 2013 Springer Science+Business Media New York. Published version deposited in accordance with the copyright policy of the publisher.
Faculty/School / Institute/Centre: Historic - Faculty of Health, Engineering and Sciences - School of Health, Nursing and Midwifery
Date Deposited: 23 Oct 2013 01:25
Last Modified: 04 Nov 2014 05:38
Uncontrolled Keywords: metabolic syndrome; seaweeds; polysaccharides; peptides; pigments; minerals
Fields of Research : 11 Medical and Health Sciences > 1111 Nutrition and Dietetics > 111103 Nutritional Physiology
03 Chemical Sciences > 0305 Organic Chemistry > 030502 Natural Products Chemistry
11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences
Identification Number or DOI: 10.1007/s11154-013-9254-8

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