Assessing heat-treatment effects on bovine cortical bones by nanoindentation

Lau, Mei-ling and Lau, Kin-tak and Ku, Harry and Bahattacharyya, Debes and Lee, Joong-Hee (2012) Assessing heat-treatment effects on bovine cortical bones by nanoindentation. Processing and Fabrication of Advanced Materials. pp. 110-113. ISSN 1022-6680

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Among different sterilization methods, heat-treatment of bone is recognized as one of the simple and practical methods to lower the human immunodeficiency virus (HIV) infection and overcome the risks of rejection and disease transfer from allograft and xenograft during bone transplantation. In order to best characterize the micro-structural mechanical property of bone after heat treatment, the nanoindentation technique was applied in this study to measure the localized elastic modulus and hardness for interstitial lamellae and osteons lamellae of bovine cortical bones at temperature 23degrees C (room temperature- pristine specimen), 37degrees C, 90 degrees C, 120 degrees C and 160 degrees C, respectively. The elastic modulus (E) and hardness (H) of interstitial lamellae obtained higher values as compared with osteons lamellae which show that interstitial lamellae are more stiff and mineralized than osteons. Moreover, as a specimen pre-heat treated at 90 degrees C, the E and H values of interstitial lamellae and osteons were closed to a pristine specimen. For a specimen pre-heat treated at 120 degrees C, both interstitial lamellae and osteons obtained an increase in E and H values. As a specimen pre-heat treated at 160 degrees C, the interstitial lamellae and osteons obtained a slight decrease in E and H values. These findings are correlated to results reported by other researchers [1, 2] that calcified collagen molecules starts to degenerate at about 120 degrees C and complete at 160 degrees C. Interestingly, when a specimen was pre-heat treated at 37 degrees C, both interstitial lamellae and osteons obtained significant decreases in E values of 57% and 40%, respectively as compared to the pristine specimen; while in H values, there was a decrease of 27.4% and 15%, respectively. Thus, this paper will investigate the mechanical properties of bovine cortical bones under various temperature ranges by nanoindentation technique.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Series title: Advanced Materials Research (Volume 410) Paper no. 84
Faculty/School / Institute/Centre: Historic - Faculty of Engineering and Surveying - Department of Mechanical and Mechatronic Engineering
Date Deposited: 16 May 2012 03:03
Last Modified: 21 Oct 2014 03:36
Uncontrolled Keywords: bovine cortical bone; heat treatment; nanoindentation; elastic modulus; hardness
Fields of Research : 09 Engineering > 0903 Biomedical Engineering > 090302 Biomechanical Engineering
06 Biological Sciences > 0608 Zoology > 060802 Animal Cell and Molecular Biology
10 Technology > 1004 Medical Biotechnology > 100499 Medical Biotechnology not elsewhere classified
Socio-Economic Objective: E Expanding Knowledge > 97 Expanding Knowledge > 970109 Expanding Knowledge in Engineering
Identification Number or DOI: 10.4028/

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