An improved detrended moving-average method for monitoring the depth of anesthesia

Nguyen-Ky, T. and Wen, Peng and Li, Yan (2010) An improved detrended moving-average method for monitoring the depth of anesthesia. IEEE Transactions on Biomedical Engineering, 57 (10). pp. 2369-2378. ISSN 0018-9294

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The detrended moving-average (DMA) method is a new approach to quantify correlation properties in nonstationary
signals with underlying trends. This paper monitored the depth of anesthesia (DoA) using modified DMA (MDMA) method. MDMA provides a power-law relation between the fluctuation function FMDMA(s) and the scale s: FMDMA(s)αsα, where α is the slope of FMDMA(s) in the logarithm scale. We applied the MDMA to monitor the DoA by computing the scaling exponent Fα and Fmin values. To validate the proposed method, we compared our results with the bispectral index (BIS) monitor. We found a close correlation between our results and BIS with r(Fmin ) = 0.9346, r^2 (Fmin ) = 0.9183, and r(Fα) = 0.9458, r^2 (Fα) = 0.8855. Our method reflects the state of consciousness of a patient undergoing general anesthesia faster than BIS as observed clinically. The minimum time delay between the BIS and Fmin trends was 12s and the maximum was 178s. Furthermore, in the case of poor signal quality, our results agreed with clinical observation, which indicates that our method can accurately estimate a patient's hypnotic state in such circumstances. Fα and Fmin trends are responsive and their movement seems similar to changes in the clinical state of the patients.

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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: © 2010 IEEE. Permanent restricted access to published version due to publisher copyright policy.
Faculty / Department / School: Historic - Faculty of Engineering and Surveying - Department of Electrical, Electronic and Computer Engineering
Date Deposited: 27 Mar 2011 08:59
Last Modified: 20 Feb 2015 04:11
Uncontrolled Keywords: depth of anesthesia; DoA; EEG; modified detrended moving-average; MDMA
Fields of Research : 09 Engineering > 0903 Biomedical Engineering > 090304 Medical Devices
09 Engineering > 0903 Biomedical Engineering > 090399 Biomedical Engineering not elsewhere classified
11 Medical and Health Sciences > 1103 Clinical Sciences > 110301 Anaesthesiology
Socio-Economic Objective: C Society > 92 Health > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920118 Surgical Methods and Procedures
Identification Number or DOI: 10.1109/TBME.2010.2053929

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