Preliminary results of meta-analysis of endoscopic retrograde cholangiopancreatography (ERCP) versus conservative treatment for gall stone pancreatitis

Burstow, Matthew J. and Yunus, Rossita M. and Khan, Shahjahan and Memon, Breda and Memon, Muhammed A. (2010) Preliminary results of meta-analysis of endoscopic retrograde cholangiopancreatography (ERCP) versus conservative treatment for gall stone pancreatitis. In: 10th Islamic Countries Conference on Statistical Sciences (ICCSS-10): Statistics for Development and Good Governance, 20-23 Dec 2009, Cairo, Egypt.

Abstract

Objectives: The aim was to conduct a meta-analysis of randomised control trials (RCTs)investigating the treatment of gallstone pancreatitis (GSP) by early ERCP versus conservative management and subsequent patient outcomes. Data Sources and Review Methods: A search of Medline, Embase, Science Citation Index, Current Contents, PubMed and the Cochrane Database of Randomised control trials identified all RCTs comparing early ERCP to conservative treatment in gallstone pancreatitis published in the English Language. The meta-analysis was prepared with reference to the guidelines given in the Quality of Reporting of Meta-analysis (QUOROM) statement. Variables that were considered the most objective to analyse were overall mortality, overall morbidity, severity of pancreatitis (mild or severe), pseudocyst formation, organ failure (renal, respiratory and cardiac), abnormal coagulation, development of pancreatic abscess/phlegmon and biliary sepsis. Results: Six trials were identified totalling 997 patients. There were significantly fewer complications in the active treatment group OR 1.78 (1.19, 2.67) with two further variables (pseudocyst formation and biliary sepsis) strongly favouring treatment but not reaching statistical significance. The other outcome variables examined showed no strong trend for either treatment regimen.


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Item Type: Conference or Workshop Item (Commonwealth Reporting Category E) (Paper)
Refereed: Yes
Item Status: Live Archive
Additional Information: Author version not held. Fulltext citation: Busrtow, M J; Yunus, R M; Khan, S; Memon, B; and Memon, M A (2010). PRELIMINARY RESULTS OF META-ANALYSIS OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY (ERCP) VERSUS CONSERVATIVE TREATMENT FOR GALL STONE PANCREATITIS. Proceedings of the Tenth Islamic Countries Conference on Statistical Sciences (ICCS-X), Volume I, 98–105.
Depositing User: Professor Shahjahan Khan
Faculty / Department / School: Historic - Faculty of Sciences - Department of Maths and Computing
Date Deposited: 29 Jan 2011 23:57
Last Modified: 03 Jul 2013 00:10
Uncontrolled Keywords: gallstone pancreatitis; meta-analysis
Fields of Research (FOR2008): 11 Medical and Health Sciences > 1103 Clinical Sciences > 110323 Surgery
Socio-Economic Objective (SEO2008): C Society > 92 Health > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920199 Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified
URI: http://eprints.usq.edu.au/id/eprint/9321

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