Study of EEGs from somatosensory cortex and Alzheimer's disease sources

Bashar, Md. R. and Li, Yan and Wen, Peng (2012) Study of EEGs from somatosensory cortex and Alzheimer's disease sources. International Journal of Biological and Life Sciences, 8 (2). pp. 62-66. ISSN 2010-3824

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Abstract

This study is to investigate the electroencephalogram (EEG) differences generated from a normal and Alzheimer’s disease (AD) sources. We also investigate the effects of brain tissue distortions due to AD on EEG. We develop a realistic head model from T1 weighted magnetic resonance imaging (MRI) using finite element method (FEM) for normal source (somatosensory cortex (SC) in parietal lobe) and AD sources (right amygdala (RA) and left amygdala (LA) in medial temporal lobe). Then, we compare the AD sourced EEGs to the SC sourced EEG for studying the nature of potential changes due to sources and 5% to 20% brain tissue distortions. We find an average of 0.15 magnification errors produced by AD sourced EEGs. Different brain tissue distortion models also generate the maximum 0.07 magnification. EEGs obtained from AD sources and different brain tissue distortion levels vary scalp potentials from normal source, and the electrodes residing in parietal and temporal lobes are more sensitive than other electrodes for AD sourced EEG.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Open Access Journal License: This work is licensed under a Creative Commons License.
Depositing User: Dr Yan Li
Faculty / Department / School: Historic - Faculty of Sciences - Department of Maths and Computing
Date Deposited: 27 Feb 2011 06:52
Last Modified: 27 Aug 2014 23:01
Uncontrolled Keywords: Alzheimer’s disease (AD); brain tissue distortion; electroencephalogram; finite element method
Fields of Research (FOR2008): 06 Biological Sciences > 0699 Other Biological Sciences > 069999 Biological Sciences not elsewhere classified
11 Medical and Health Sciences > 1109 Neurosciences > 110999 Neurosciences not elsewhere classified
11 Medical and Health Sciences > 1103 Clinical Sciences > 110316 Pathology (excl. Oral Pathology)
Socio-Economic Objective (SEO2008): C Society > 92 Health > 9202 Health and Support Services > 920203 Diagnostic Methods
C Society > 92 Health > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920112 Neurodegenerative Disorders Related to Ageing
URI: http://eprints.usq.edu.au/id/eprint/8848

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