Study of biodegradation of pure magnesium

Ren, Yibin and Wang, Hao and Huang, Jingjing and Zhang, Bingchun and Yang, Ke (2007) Study of biodegradation of pure magnesium. In: ASBM7: 7th Asian Symposium on Biomedical Materials , 20-23 Aug 2006, Jeju, Korea.

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Official URL: http://www.scientific.net/KEM.342-343.601

Identification Number or DOI: doi: 10.4028/www.scientific.net/KEM.342-343.601

Abstract

Magnesium and its alloys are possible to develop new type of biodegradable medical magnesium alloys by using their active corrosion potential. The bio-corrosion properties of the high pure magnesium in the Hank's solution were investigated in this paper, the results showed that high pure magnesium had a low corrosion rate and hydrogen release in Hank's solution, when the pH value of solution was controlled at 7.5, the corrosion rate was under 0.2mm/year, the production of hydrogen was about 0.15ml/cm2, and if the solution wasn't controlled on pH value, the corrosion rate was about 0.02 mm/year, production of hydrogen was about 0.1 ml/cm2. Result of in vitro Kinetic clotting time test and animal implant prep-test showed that High pure magnesium had good thromboresistant property and tissue compatibility, pure magnesium can biodegrade lowly in animal body and formed surface apatite, which proportion of Ca/P was similar with bone tissue.

Item Type:Conference or Workshop Item (Commonwealth Reporting Category E) (Paper)
Additional Information:Electronic version not held.
Uncontrolled Keywords:biocompatibility; biodegradation; biomaterial; corrosion; magnesium
Fields of Research (FOR2008):09 Engineering > 0903 Biomedical Engineering > 090304 Medical Devices
03 Chemical Sciences > 0399 Other Chemical Sciences > 039904 Organometallic Chemistry
09 Engineering > 0912 Materials Engineering > 091207 Metals and Alloy Materials
Subjects:UNSPECIFIED
Socio-Economic Objective (SEO2008):B Ecomonic Development > 86 Manufacturing > 8611 Basic Metal Products (incl. Smelting, Rolling, Drawing and Extruding) > 861199 Basic Metal Products (incl. Smelting, Rolling, Drawing and Extruding) not elsewhere classified
C Society > 92 Health > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920118 Surgical Methods and Procedures
ID Code:8479
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Deposited On:21 Jul 2010 21:08
Last Modified:02 May 2012 16:51

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