Diurnal variation in peripheral (hair) vs central (saliva) HPA axis cortisol concentrations

Sharpley, Christopher F. and Kauter, Kathleen G. and McFarlane, James R. (2010) Diurnal variation in peripheral (hair) vs central (saliva) HPA axis cortisol concentrations. Clinical Medicine Insights: Endocrinology and Diabetes, 3. pp. 9-16. ISSN 1179-5514

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Abstract

Cortisol concentrations in hair and saliva collected from male and female adults over a 15-hour period were compared for differences in overall level and cyclic pattern. Typical diurnal fluctuations were noted for both salivary and hair cortisol, with some individual differences that are congruent with the previous literature. Issues of the link between central and peripheral HPA axes are raised for discussion and further investigation, and hypothetical explanations for the diurnal variability shown in these two sets of cortisol secretion patterns are discussed from an evolutionary advantage perspective.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: This article is available from http://www.la-press.com. © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
Depositing User: Ms Debbie White
Faculty / Department / School: Historic - Faculty of Sciences - Department of Biological and Physical Sciences
Date Deposited: 15 Dec 2010 11:38
Last Modified: 25 Aug 2014 02:56
Uncontrolled Keywords: cortisol; hair; diurnal; peripheral HPA axis
Fields of Research (FOR2008): 11 Medical and Health Sciences > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified
06 Biological Sciences > 0606 Physiology > 060699 Physiology not elsewhere classified
11 Medical and Health Sciences > 1116 Medical Physiology > 111699 Medical Physiology not elsewhere classified
Socio-Economic Objective (SEO2008): E Expanding Knowledge > 97 Expanding Knowledge > 970111 Expanding Knowledge in the Medical and Health Sciences
Identification Number or DOI: doi: 10.4137/CMED.S4350
URI: http://eprints.usq.edu.au/id/eprint/7766

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