Iyer, Abishek and Panchal, Sunil and Poudyal, Hemant and Brown, Lindsay (2009) Potential health benefits of Indian spices in the symptoms of metabolic syndrome: a review. Indian Journal of Biochemistry and Biophysics, 46 (6). pp. 467-481. ISSN 0301-1208
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Spices used in Indian cooking have a long history use as medicines to prevent and treat diseases. Many studies have confirmed that spices can be useful medicines, but the major challenge is now to provide scientific evidence and plausible mechanisms for their therapeutic responses. This review focuses on the therapeutic potential for Indian spices to treat multiple symptoms of the metabolic syndrome such as insulin resistance, diabetes, obesity, altered lipid profile and hypertension. The metabolic syndrome is prevalent and has become an important financial burden to the healthcare system in both developed and developing countries. Inflammation and oxidative stress have been proposed as initiators of the metabolic stress, especially of insulin resistance. Natural products with anti-inflammatory and anti-oxidant properties are found in spices. Adequate doses of these compounds may be effective in treating the metabolic syndrome. Testing these potential treatments requires adequate animal models, usually rodents, so the limitations of these models are important. Furthermore, this review highlights the need for adequate legislation and regulation to ensure the safety and success of evidence-based functional foods and nutraceuticals.
|Item Type:||Article (Commonwealth Reporting Category C)|
|Additional Information:||Items in NISCAIR Online Periodicals Repository are protected by copyright, with all rights reserved, unless otherwise indicated.|
|Uncontrolled Keywords:||spices; diabetes; metabolic syndrome; inflammation; oxidative stress; nutraceuticals; food safety|
|Fields of Research (FOR2008):||11 Medical and Health Sciences > 1104 Complementary and Alternative Medicine > 110499 Complementary and Alternative Medicine not elsewhere classified|
11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110107 Metabolic Medicine
03 Chemical Sciences > 0305 Organic Chemistry > 030502 Natural Products Chemistry
|Socio-Economic Objective (SEO2008):||C Society > 92 Health > 9204 Public Health (excl. Specific Population Health) > 920412 Preventive Medicine|
|Deposited On:||12 Jun 2010 12:52|
|Last Modified:||05 Sep 2012 14:23|
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