(Z,Z)-3,6-Bis[(3,4,5-trimethoxyphenyl)-methylene]piperazine-2,5-dione

Loughlin, Wendy A. and Marshall, Raymond L. and Fairfull-Smith, Kathryn E. and Healy, Peter C. (2005) (Z,Z)-3,6-Bis[(3,4,5-trimethoxyphenyl)-methylene]piperazine-2,5-dione. Acta Crystallographica Section E: Structure Reports Online, 61 (5). O1443-O1445. ISSN 1600-5368

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Official URL: http://dx.doi.org/10.1107/S1600536805012316

Identification Number or DOI: doi: 10.1107/S1600536805012316

Abstract

The title compound, C24H26N2O8, is a derivative of neihumicin, a cytotoxic antibiotic from Micromonospora neihuensis. The compound crystallizes as discrete molecules with crystallographic inversion symmetry. Intermolecular N-H••• O hydrogen bonds yield polymeric chains along the c axis. The trimethoxyphenylmethylene side chain is found to be in a Z configuration about the C=C double bond.

Item Type:Article (Commonwealth Reporting Category C)
Additional Information:Access to paper currently restricted pending permission from publisher.
Uncontrolled Keywords:Micromonospora neihuensis; neihumicin
Fields of Research (FOR2008):03 Chemical Sciences > 0399 Other Chemical Sciences > 039999 Chemical Sciences not elsewhere classified
Subjects:250000 Chemical Sciences
Socio-Economic Objective (SEO2008):UNSPECIFIED
ID Code:454
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Deposited On:17 Feb 2010 20:29
Last Modified:07 Jul 2011 14:57

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