Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp.

Michael, Adam P. and Grace, Emily J. and Kotiw, Mike and Barrow, Russell A. (2002) Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp. Journal of Natural Products, 65 (9). pp. 1360-1362. ISSN 0163-3864

Abstract

A new antibiotic polyene tetramic acid, ravenic acid (2), has been isolated from the mycelia of a cultured fungus, Penicillium sp. The structure of ravenic acid was determined by detailed spectroscopic analysis and the major isomer identified as possessing (3Z, 7E, 9E, 11E, 13E) stereochemistry.


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Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Permanent restricted access to paper due to publisher copyright restrictions.
Depositing User: Assoc Prof Mike Kotiw
Faculty / Department / School: Historic - Faculty of Sciences - Department of Biological and Physical Sciences
Date Deposited: 23 Jan 2008 03:11
Last Modified: 07 Nov 2013 06:35
Uncontrolled Keywords: ravenic acid; penicillium sp; drug isolation; drug structure; mycelium; proton nuclear magnetic resonance; spectroscopy; stereochemistry; X ray diffraction
Fields of Research (FOR2008): 06 Biological Sciences > 0605 Microbiology > 060505 Mycology
11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110101 Medical Biochemistry: Amino Acids and Metabolites
10 Technology > 1004 Medical Biotechnology > 100403 Medical Molecular Engineering of Nucleic Acids and Proteins
Socio-Economic Objective (SEO2008): E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences
Identification Number or DOI: doi: 10.1021/np0200358
URI: http://eprints.usq.edu.au/id/eprint/3622

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