Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp.

Michael, Adam P. and Grace, Emily J. and Kotiw, Mike and Barrow, Russell A. (2002) Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp. Journal of Natural Products, 65 (9). pp. 1360-1362. ISSN 0163-3864

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Official URL: http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/2002/65/i09/abs/np0200358.html

Identification Number or DOI: doi: 10.1021/np0200358

Abstract

A new antibiotic polyene tetramic acid, ravenic acid (2), has been isolated from the mycelia of a cultured fungus, Penicillium sp. The structure of ravenic acid was determined by detailed spectroscopic analysis and the major isomer identified as possessing (3Z, 7E, 9E, 11E, 13E) stereochemistry

Item Type:	Article (Commonwealth Reporting Category C)
Additional Information:	Permanent restricted access to paper due to publisher copyright restrictions.
Uncontrolled Keywords:	ravenic acid; penicillium sp; drug isolation; drug structure; mycelium; proton nuclear magnetic resonance; spectroscopy; stereochemistry; X ray diffraction
Fields of Research (FOR2008):	06 Biological Sciences > 0605 Microbiology > 060505 Mycology 11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110101 Medical Biochemistry: Amino Acids and Metabolites 10 Technology > 1004 Medical Biotechnology > 100403 Medical Molecular Engineering of Nucleic Acids and Proteins
Subjects:	320000 Medical and Health Sciences > 320500 Pharmacology and Pharmaceutical Sciences > 320599 Pharmacology not elsewhere classified
Socio-Economic Objective (SEO2008):	E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences
ID Code:	3622
Deposited By:	Assoc Prof Mike Kotiw
Deposited On:	23 Jan 2008 13:11
Last Modified:	23 Nov 2011 12:39

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