Temporal relationship between the auditory brainstem response and focal responses of auditory nerve root and cochlear nucleus during development in the tammar wallaby (Macropus eugenii)

Liu, G. B. and Hill, K. G. and Mark, R. F. (2001) Temporal relationship between the auditory brainstem response and focal responses of auditory nerve root and cochlear nucleus during development in the tammar wallaby (Macropus eugenii). Audiology and Neuro-Otology, 6 (3). pp. 140-153. ISSN 1420-3030

Abstract

Thirty-two pouch-young tammar wallabies were used to discover the generators of the auditory brainstem response (ABR) during development by the use of simultaneous ABR and focal brainstem recordings. A click response from the auditory nerve root (ANR) in the wallaby was recorded from postnatal day (PND) 101, when no central auditory station was functional, and coincided with the ABR, a simple positive wave. The response of the cochlear nucleus (CN) was detected from PND 110, when the ABR had developed 1 positive and 1 negative peak. The dominant component of the focal ANR response, the N1 wave, coincided with the first half of the ABR P wave, and that of the focal CN response, the N1 wave, coincided with the later two thirds. In older animals, the ANR response coincided with the ABR's N1 wave, while the CN response coincided with the ABR's P2, N2 and P3 waves, with its contribution to the ABR P2 dominant. The protracted development of the marsupial auditory system which facilitated these correlations makes the tammar wallaby a particularly suitable model.


Statistics for USQ ePrint 3216
Statistics for this ePrint Item
Item Type: Article (Commonwealth Reporting Category C)
Refereed: Yes
Item Status: Live Archive
Additional Information: Copyright © 2001 S. Karger AG, Basel. The article relating to this record is copyright protected. Any distribution without written consent from S. Karger AG, Basel is a violation of the copyright.
Depositing User: Dr Guang Liu
Faculty / Department / School: Historic - Faculty of Sciences - Department of Biological and Physical Sciences
Date Deposited: 04 Feb 2008 03:11
Last Modified: 17 Sep 2013 05:36
Uncontrolled Keywords: auditory development; wallaby; Macropus eugenii; auditory brainstem response
Fields of Research (FOR2008): 11 Medical and Health Sciences > 1109 Neurosciences > 110906 Sensory Systems
11 Medical and Health Sciences > 1109 Neurosciences > 110903 Central Nervous System
06 Biological Sciences > 0608 Zoology > 060805 Animal Neurobiology
Socio-Economic Objective (SEO2008): E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences
Identification Number or DOI: doi: 10.1159/000046821
URI: http://eprints.usq.edu.au/id/eprint/3216

Actions (login required)

View Item Archive Repository Staff Only