Michael, Adam P. and Grace, Emily J. and Kotiw, Michael and Barrow, Russell A. (2003) Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp. Australian Journal of Chemistry, 56 (1). pp. 13-15. ISSN 0004-9425
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Identification Number or DOI: doi: 10.1071/CH02021
Isochromophilone IX, a novel antibiotic active component was isolated from a penicillium species and investigated. Isochromophilone IX displays a specific rotation with the same sign as isochromophilone VI. It was found that isochromophilone represents the first occurrence of an γ-amino butyric acid (GABA) containing metabolite among only four naturally occuring members of this structure class.
|Item Type:||Article (Commonwealth Reporting Category C)|
|Additional Information:||Permanent restricted access to paper due to publisher copyright restrictions. (CSIRO)|
|Uncontrolled Keywords:||amino acids; fungi; high performance liquid chromatography; isomers; mass spectrometry; metabolites|
|Fields of Research (FOR2008):||06 Biological Sciences > 0605 Microbiology > 060501 Bacteriology|
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11 Medical and Health Sciences > 1101 Medical Biochemistry and Metabolomics > 110101 Medical Biochemistry: Amino Acids and Metabolites
10 Technology > 1004 Medical Biotechnology > 100403 Medical Molecular Engineering of Nucleic Acids and Proteins
|Socio-Economic Objective (SEO2008):||E Expanding Knowledge > 97 Expanding Knowledge > 970106 Expanding Knowledge in the Biological Sciences|
|Deposited On:||30 Nov 2007 21:47|
|Last Modified:||07 Jul 2012 22:47|
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